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Moreover, using proton magnetic resonance spectroscopic imaging with (1)H MRSI, significantly higher levels of ventricular cerebrospinal fluid lactate are found in ME/CFS patients compared to healthy controls (203)

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Collagen and Extracellular Matrix Remodeling GHK-Cu activates fibroblasts, increasing the synthesis of: Type I and III collagen Elastin Proteoglycans Glycosaminoglycans (including hyaluronic acid) This mechanism helps restore structural integrity, improving firmness, elasticity, and volume over time